Job details
Job type full-time
Full job description
Associate scientist, process science - upstream (onsite)
Partner therapeutics (ptx) is a commercial biopharmaceutical company committed to improving the lives of patients with cancer and other serious diseasesOur dedicated team brings a rigorous approach to science, establishes deep partnerships with medical and scientific communities, and works tirelessly to expand potential treatment options and address unmet medical needs.
Position description
The upstream process science department is a group of scientists and subject matter experts who specialize in the development, maintenance, remediation, and transfer of the production processes used in cgmp commercial manufacturingThis position is primarily a lab-based role which requires hands-on execution of upstream development, optimization and characterization experiments using small-scale models, along with analysis and interpretation of experimental data.
Key responsibilities
Lead upstream fermentation/cell culture experiments for process development and optimization
Assist in designing experiments related to development, scale-up, scale-down and characterization of fermentation and primary recovery processes
Interpret results and design studies for process improvements using statistical design of experiments (doe) methodology
Provides upstream technical support for cgmp manufacturing
Provides scientific technical support for technology transfer of processes to manufacturing
Participates on working teams related to continuous improvements for the business
Communicates work through oral presentations and written documentation, including technical reports
Leads set-up, maintenance and operation of bioprocess equipment including: spectrophotometer, ysi, rp-hplc, shake flasks, fermenters and tangential flow filtration
Preparation of media and buffers
Process data entry and data analysis
Qualifications
A minimum of a bachelor’s degree in biology, biochemistry, chemistry, bioengineering, chemical engineering or equivalently related field with 6+ years of directly relevant process sciences and/or upstream experienceAlternatively, a master’s degree with a minimum of 4+ years of process sciences and/or upstream experience required.
Experience with yeast fermentation/cell culture operations and recovery processes, including shake flask expansion, small and large scale fermenter/bioreactor production, scale-up/scale-down, process transfer, and tangential flow filtration (tff)
Knowledge of design of experiments (doe) and statistical data analysis
Proficient in cell culture and bioreactor operations with proper aseptic technique
Detail-oriented with the ability to work with minimal supervision, and complete written and verbally- assigned tasks following specific procedures
Ability to independently make decisions based on data, scientific knowledge and sound judgement
Team player with a can-do attitude, intellectual curiosity, organized, strong time management skills, ability to be flexible to business needs and self-starter
Excellent communication skills both written and oral
Maintain a safe work environment in accordance with policies, procedures and regulations
In addition to medical, dental, vision, fsa/dca, hra, disability, and life insurance coverage, all full-time, regular partners enjoy a casual, and hybrid or remote workplace program for many rolesWe offer a terrific compensation/benefits/perks package which includes pre-ipo options, annual cash bonuses, 401k matching, free parking or seattle-area orca pass, tuition assistance, plus rewards for achievement and contributionTo support a healthy work-life balance we also provide a gym subsidy, wellness participation programs, and a generous vacation, sick, and holiday paid time off program in addition to a paid shutdown between the christmas and new year’s holidays.
Partner therapeutics is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, age, national origin, veteran status, marital status, sexual orientation, gender identity, disability or any other category prohibited by local, state or federal lawThis policy applies to all aspects of employment, including recruitment, placement, promotion, transfer, demotion, compensation, benefits, social and recreational activities, and termination.
Job type: full-time
Work location: multiple locations
